SAN FRANCISCO (MarketWatch) -- Canadian stocks headed downward early Wednesday, with Toronto's benchmark equities index falling 45 points, or 0.4%, to 11,621. A 1.8% loss in the materials sector /zigman2/quotes/210598474/delayed XX:TORGC195 +2.77% and 0.4% decline in industrial stocks /zigman2/quotes/210598464/delayed XX:TORGC193 +0.74% weighed on the market. On the economic front, manufacturing in July reportedly slowed, with the RBC Canadian Manufacturing Purchasing Managers Index slipping to 53.1, from 54.8 the previous month. In earnings, Talisman Energy Inc. posted a 72% lower second-quarter profit, while Torstar Corp.'s second-quarter net income tumbled 68%. Meanwhile, the greenback fell against the Canadian currency /zigman2/quotes/210561978/realtime/sampled USDCAD -0.4881% , with one U.S. dollar purchasing C$1.0021 vs. C$1.0033 Tuesday.