European stocks opened flat on Wednesday, with investors weighing up a fresh batch of earnings and data showing Germany factory orders saw the biggest drop record in March. The Stoxx Europe 600 index /zigman2/quotes/210599654/delayed XX:SXXP -1.02% slipped 0.1% to 334.96, after the index broke a three-session losing streak on Tuesday with a more than 2% gain. Investors continue to keep a concerned eye on the pandemic, after news that the U.K. has now replaced Italy with the biggest death toll in Europe. A fresh batch of earnings showed companies continue to struggle with virus fallout. Shares of BMW /zigman2/quotes/209548467/delayed DE:BMW +0.02% fell nearly 5% after warning of significantly lower profit in 2020, while shares of chemical group Arkema SA /zigman2/quotes/200304947/delayed FR:AKE -1.77% sank 4% after posting revenue and earnings falls. U.S. equity futures headed the other direction, with Dow futures climbing 179 points after President Donald Trump said the country would have to keep reopening businesses even if it means more deaths due to the coronavirus.