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Jan. 24, 2021, 1:50 p.m. EST

Wuhan, China, marks a year since it entered lockdown as Ground Zero of coronavirus epidemic

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Associated Press

Nearly a year to the day after the Chinese city of Wuhan went into lockdown to contain a virus that had already escaped, President Joe Biden began putting into effect a new war plan for fighting the outbreak in the U.S., Germany topped 50,000 deaths, and Britain closed in on 100,000.

From the MarketWatch archives (Jan. 25, 2020): 4 surprising facts about China’s new mystery illness

The anniversary of the lockdown Saturday comes as more contagious variants of the coronavirus spread and efforts to vaccinate people against COVID-19 have been frustrated by disarray and limited supplies in some places. The scourge has killed over 2 million people worldwide.

Wall Street Journal: Anger at China’s COVID-19 response smolders in Wuhan

In the U.S., which has the world’s highest death toll at over 410,000, Dr. Anthony Fauci said a lack of candor about the threat under President Donald Trump probably cost lives.

Fauci, who was sidelined by Trump, is now the chief medical adviser to Biden in an ambitious effort to conquer the virus. He told CNN that the Trump administration delayed getting sound scientific advice to the country.

“When you start talking about things that make no sense medically and no sense scientifically, that clearly is not helpful,” he said.

Biden signed a series of executive orders Thursday to mount a more centralized attack on the virus and has vowed to vaccinate 100 million people in his first 100 days, a number some public health experts say is not ambitious enough.

Dr. Eric Topol, head of the Scripps Research Translational Institute, said the U.S. should aim to vaccinate 2.5 million a day.

“This was already an emergency,” Topol said, but with more contagious mutations of the virus circulating, “it became an emergency to the fourth power.”

In Britain, where a more transmissible variant of the virus is raging, the death toll hit close to 96,000, the highest in Europe. And the government’s chief scientific adviser warned that the mutated version might be deadlier than the original.

Patrick Vallance cautioned that more research is needed but that the evidence suggests that the variant might kill 13 or 14 people out of every 1,000 infected, compared with 10 in 1,000 from the original.

Germany extended its lockdown this week until Feb. 14 amid concern about the mutant viruses.

Some nations are imposing or considering new travel restrictions for the same reason. France said it will require a negative test from travelers arriving from other European Union countries starting Sunday. Canada said it may force visitors to quarantine in a hotel at their own expense upon arrival.

Canadian Prime Minister Justin Trudeau warned the country: “No one should be taking a vacation abroad right now. If you’ve still got one planned, cancel it. And don’t book a trip for spring break.”

In another apparent setback, AstraZeneca said it will ship fewer doses of its vaccine than anticipated to the 27-country EU because of supply chain problems.

Amid the crisis, Japan is publicly adamant it will hold the postponed Olympics in July. Many experts believe that to pull that off, the nation will have to vaccinate all 127 million citizens, an effort that may not even begin until late February.

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