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9:01 a.m. March 11, 2021 - By Paul Brandus
For seniors, it’s a double pandemic — COVID-19 and crushing isolation Tips on how to weather the stormTips on how to weather the storm
9:04 a.m. March 10, 2021 - By Jaimy Lee
Vertex to begin Phase 1/2 trial of treatment for people with type 1 diabetesShares of Vertex Pharmaceuticals Inc. were down 0.2% in trading on Wednesday after the company said it started an early-stage clinical trial for its experimental treatment for people with type 1 diabetes. It also said the therapy received a fast-track designation from the Food and Drug Administration. The Phase 1/2, single-arm, open-label study will be conducted at multiple sites in the U.S. and aims to enroll 17 participants. Vertex gained access to the therapy through its roughly $1 billion acquisition of Semma Therapeutics Inc. in 2019. Vertex's stock is down 7.4% over the past year, while the S&P 500 has rallied 41.1%. The clinical trial is a Phase 1/2, single-arm, open-label study in patients who have T1D with impaired hypoglycemic awareness and severe hypoglycemia. This will be a sequential, multi-part clinical trial to evaluate the safety and efficacy of different doses of VX-880. Approximately 17 patients will be enrolled in the clinical trial. About Type 1 Diabetes T1D results from the autoimmune destruction of insulin-producing islet cells in the pancreas, leading to loss of insulin production and impairment of blood glucose control. The absence of insulin leads to abnormalities in how the body processes nutrients, leading to high blood glucose levels. High blood glucose can lead to diabetic ketoacidosis and over time, to complications such as kidney disease/failure, eye disease (including vision loss), heart disease, stroke, nerve damage and even death. Due to the limitations and complexities of insulin delivery systems, it can be difficult to achieve and maintain balance in glucose control in patients with T1D. Hypoglycemia often results because of the difficulty in balancing the different factors that impact glucose levels, including insulin, diet and exercise. Hypoglycemia remains a critical limiting factor in glycemic management, and severe hypoglycemia can cause loss of consciousness, coma, seizures, injury, and can be fatal. Over time, patients with T1D can develop impaired awareness of hypoglycemia, meaning they are no longer able to perceive the early signs of a hypoglycemic event, which can be dangerous and result in life threatening events. There are currently limited treatment options beyond insulin for the management of T1D.
10:12 a.m. Dec. 2, 2020 - By Quentin Fottrell
‘Cytokine Storm’ — the ‘intriguing’ similarity between COVID-19 and the 1918 influenza A hyperinflammatory immune response to the influenza of 1918 was seen as one reason healthy people were so hard hit. How big a role has it played in 2020?A hyperinflammatory immune response to the influenza of 1918 was seen as one reason healthy people were so hard hit. How big a role has it played in 2020?
4:44 a.m. Dec. 2, 2020 - By Jacob Passy
‘I thought, You’re kicking my dog out, too?’ The legally messy eviction of a North Carolina single mother Thousands of evictions are moving forward across the country, even though the CDC has ostensibly banned themThousands of evictions are moving forward across the country, even though the CDC has ostensibly banned them.
6:10 a.m. Nov. 13, 2020 - By Liz Weston
This is what it could cost you if Obamacare is thrown out by the Supreme Court Even if you get to keep your health insurance, you could pay the priceIf the Supreme Court throws out the Affordable Care Act, your finances and your future could pay the price.
10:29 a.m. Nov. 11, 2020 - By Ciara Linnane
Coronavirus update: U.S. sets record for hospitalizations with 17 states at peak levels; ‘Wisconsin,’ pleads Gov. Tony Evers, ‘this is serious!’ North Dakota’s hospital system is at 100% capacity, and state is allowing health-care workers who have tested positive to stay on the job and treat COVID patientsThe U.S. case tally for the coronavirus illness COVID-19 climbed above 10.3 million on Wednesday, as hospitalizations set a record with Midwest hospitals now fuller than the South was during its summer peak.
2:13 p.m. Nov. 3, 2020 - By Ciara Linnane
Coronavirus update: U.S. headed for ‘most deadly phase’ of pandemic, says Dr. Birx, contradicting Trump’s insistence it has rounded a corner ‘We are entering the most concerning and most deadly phase of this pandemic … leading to increasing mortality,’ Dr. Birx warnsThe U.S. death toll from the coronavirus illness COVID-19 climbed toward 232,000 on Tuesday as American voters headed to the poll to elect a president, and the head of the White House Task Force created to manage the pandemic issued a dire warning.
12:07 p.m. Oct. 30, 2020 - By Nicole Lyn Pesce
Watch: Georgia debate gets heated as Sen. David Perdue is labeled a ‘crook’ by rival Jon Ossoff Ossoff calls incumbent a coward as Perdue pulls out of third debate, which had been set for SundayThe third debate has been canceled after Perdue pulled out
2:17 a.m. Oct. 28, 2020 - By Ciara Linnane
Coronavirus update: U.S. case tally tops 8.7 million and marks seven-day record, with more than 20 states seeing most new cases since start of the outbreak Dr. Birx says North Dakotans’ failure to wear face masks is ‘deeply unfortunate’ as the Dakotas suffer worst case numbers measured per capitaThe U.S. case tally for the coronavirus illness COVID-19 climbed above 8.7 million on Tuesday, with more than 20 states counting record numbers of new infections, as more business curfews were announced to combat the spread.
5:25 a.m. Oct. 24, 2020 - By Nicole Lyn Pesce
Jeff Bridges is one of the 85,000-plus lymphoma cases expected in the U.S. this year What to know about the most common type of blood cancer almost 800,000 Americans are living with or in remission fromWhat to know about the most common type of blood cancer almost 800,000 Americans are living with or in remission from
2:08 a.m. Oct. 22, 2020 - By Ciara Linnane
Coronavirus update: CDC says nearly 300,000 excess American deaths have occurred during pandemic CDC study finds biggest percentage rise in excess deaths were in those aged 25 to 44, Blacks and Hispanics hit disproportionatelyThe U.S. death toll from the coronavirus illness COVID-19 rose above 221,000 on Wednesday, according to data aggregated by Johns Hopkins University, and the nation’s leading public health agency estimated that the pandemic has contributed to the deaths of almost 300,000 Americans, including fatalities that would not have happened without the virus.
3:27 a.m. Oct. 18, 2020 - By Quentin Fottrell
‘COVID-19 remains a serious public-health threat’: New Yorkers don’t have hope that their city will recover anytime soon The impact of COVID-19, the disease caused by SARS-CoV-2, continues to weigh most heavily on people of color in New YorkThe impact of COVID-19, the disease caused by SARS-CoV-2, continues to weigh most heavily on people of color in New York.
12:57 a.m. Oct. 10, 2020 - By Andrew Keshner
Harris-Pence debate put spotlight on 54 million Americans with pre-existing conditions — and how they would be covered if Obamacare falls Vice President Mike Pence said the Trump administration will protect people with pre-existing conditions, but didn’t get specific.Vice President Mike Pence said the Trump administration will protect people with pre-existing conditions, but didn’t get specific.
10:26 p.m. Oct. 6, 2020 - By Quentin Fottrell
‘Don’t ever, ever underestimate the potential of the pandemic’: 5 reasons scientists say you should be afraid of COVID-19 President Trump left Walter Reed Monday and returned to the White House, telling the nation, ‘Don’t be afraid of it.’ Anthony Fauci later cautioned the president’s condition ‘could have a reversal.’President Trump left Walter Reed Monday and returned to the White House, telling the nation, ‘Don’t be afraid of it.’ Anthony Fauci later cautioned the president’s condition ‘could have a reversal.’
12:51 p.m. Oct. 4, 2020 - By Quentin Fottrell
Why Trump is at higher risk of more severe illness from unpredictable COVID-19 Most COVID-related fatalities are over 70. Genes that are a major factor allowing the virus access to heart cells are more active in older peopleMost COVID-related fatalities are over 70. Genes that are a major factor allowing the virus access to heart cells are more active in older people.
12:01 p.m. Oct. 3, 2020 - Associated Press
Presidents have often concealed or lied about health problems throughout U.S. history In some cases the issues were minor, in other cases grave, and sometimes it took decades for the public to learn the truthThroughout American history, an uncomfortable truth has emerged: Presidents have lied about their health.
12:34 p.m. Oct. 1, 2020 - Associated Press
Flu vaccine expected to be in high demand as U.S. and Europe aim to ward off ‘twindemic’ A record number of doses are on the way — between 194 million and 198 million for the U.S. aloneA record number of doses are on the way — between 194 million and 198 million for the U.S. alone.
6:05 a.m. Sept. 30, 2020 - By Wendy Helfenbaum
‘Anyone can make money.’ This retired Wall Street investor wants to motivate Americans to do something else: Get off the couch After 30 years of no exercise while building a successful investment career, Jim Owen wants to show it’s never too late to become healthierHis purpose and his legacy now is inspiring older adults to become healthier and more active.
12:18 a.m. Sept. 25, 2020 - By Quentin Fottrell
My wife and I live with my dying mother. My brothers and I will inherit her home. Should I ask her to sell it — and move in with me? ‘If she agrees to move, and puts the money in her bank account — a joint account with one of her grandchildren — what happens to the money? She gave that grandchild survivorship rights’‘If she agrees to move, and puts the money in her bank account — a joint account with one of her grandchildren — what happens to the money? She gave that grandchild survivorship rights.’
11:30 a.m. Sept. 24, 2020 - By Nicole Lyn Pesce
Whole Foods founder blames obesity crisis on ‘ignorance,’ not food prices — ‘We’ve opened stores in poor areas’ John Mackey said ‘the whole world is getting fat’ in a New York Times interview, making the pandemic worseJohn Mackey said ‘the whole world is getting fat’ in a New York Times interview, making the pandemic worse
9:42 p.m. Sept. 23, 2020 - Associated Press
As Trump continues to press for coronavirus vaccine by Election Day, public health officials vow ‘no cutting corners’A huge international study of a COVID-19 vaccine that aims to work with just one dose is getting underway as top U.S. health officials sought Wednesday to assure a skeptical Congress and public that they can trust any shots the government ultimately approves.
9:12 p.m. Sept. 23, 2020 - Associated Press
COVID-19 is the new pre-existing condition, Democratic senators warn as Republicans remain committed to vanquishing ‘Obamacare’ Says Sen. Chris Murphy of Connecticut: ‘We will see [insurance] rates skyrocket for anybody who has had COVID’Says Sen. Chris Murphy, D-Conn.: “We will see [insurance] rates skyrocket for anybody who has had COVID.”
4:48 a.m. Sept. 23, 2020 - By Wendy Schuman
My grandchildren give meaning to my life…When will it be safe to see them again? Holding out hope, and trying to connect emotionally through virtual meansI miss our grandkids, I yearn for them — and I admit I sometimes feel depressed that I can’t see them.
11:05 a.m. Sept. 17, 2020 - By Ciara Linnane
Coronavirus update: Global cases near 30 million; Trump contradicts CDC head on vaccine timetable and again derides face masks WHO official says it’s important to have ‘consistent messaging’ on pandemic from all public officials The number of confirmed cases of the coronavirus that causes COVID-19 worldwide continued to head toward 30 million on Thursday, and the U.S. case tally climbed above 6.6 million, as President Donald Trump contradicted the head of the main U.S. public health agency to insist a vaccine would be ready in weeks.
3:53 a.m. Sept. 17, 2020 - By Jaimy Lee
Rigel's stock jumps on start of Phase 2 trial for investigational COVID-19 treatmentShares of Rigel Pharmaceuticals Inc. were up 10.4% in premarket trading on Thursday after the company said it had started a randomized, double-blind, placebo-controlled Phase 2 clinical trial evaluating Tavalisse as a treatment for hospitalized COVID-19 patients. The study, which is sponsored by the National Heart, Lung, and Blood Institute, will enroll about 60 patients and consider disease progression as well as safety and efficacy. "Expanding our clinical effort into this second trial in COVID-19 related lung injuries is critical," Rigel CEO Raul Rodriguez said in a news release. The Food and Drug Administration approved Tavalisse as a treatment for chronic immune thrombocytopenia in adults in 2018. Shares of Rigel have gained 16.8% so far this year, while the S&P 500 is up 4.8%.
8:07 a.m. Sept. 16, 2020 - By Howard Gold
Long-term care insurance: There’s no good alternative Other options can be pricey and may not cover what you needOther options can be pricey and may not cover what you need
6:00 a.m. Sept. 16, 2020 - Associated Press
Oregon, Washington and California are struggling under the most unhealthy air on the planet With smoke seeping under doors and through AC vents, bad air from the West’s fires won’t ease up for days or weeksDangerously dirty air spewing from the West Coast wildfires is seeping into homes and businesses, sneaking into cars through air conditioning vents and preventing people already shut away by the coronavirus pandemic from enjoying a walk or trip to the park.
2:45 p.m. Sept. 14, 2020 - By Elisabeth Buchwald
Amazon sellers are charging up 14 times the usual price on some household products and student debt is fueling the Black-white wealth gap Monday’s top personal finance stories Monday’s top personal finance stories Monday’s top personal finance stories
2:12 a.m. Sept. 14, 2020 - By Quentin Fottrell
‘We were frustrated and afraid’: Some COVID-19 patients suffer lung and heart damage, but there’s encouraging news for these ‘long haulers’ Two papers presented at the European Respiratory Society International Congress examined patients who were suffering health aftereffects of coronavirusTwo papers presented at the European Respiratory Society International Congress examined patients who were suffering health aftereffects of coronavirus.
12:03 p.m. Sept. 9, 2020 - By Bianca Flowers
How Black doctors are answering the call to reform medical education — and bringing COVID-19 vaccine trials to communities of color Patients of color have been ignored in medical textbooks for decades. Black doctors and students say the restructuring of the curriculum is necessary to change the culture of medicine in the classroom — and the examination room.Patients of color have been ignored in medical textbooks for decades. Black doctors and students say the restructuring of the curriculum is necessary to change the culture of medicine in the classroom — and the examination room.
5:21 p.m. Sept. 2, 2020 - Associated Press
Tom Seaver, Hall of Fame pitcher and ‘Miracle Mets’ hero, dies at 75 3-time Cy Young winner dies from complications of dementia, COVID-19om Seaver, the galvanizing leader of the “Miracle Mets” 1969 championship team and a pitcher who personified the rise of expansion teams during an era of radical change for baseball, has died. He was 75.
2:47 a.m. Aug. 31, 2020 - Associated Press
Trump convention tamps down thoughts of coronavirus and ramps up rhetoric of fear Federal guidelines on social distancing and wearing masks to fight the spread of the deadly virus were emphatically ignored, as, for the most part, were concerns about violating the Hatch ActThe federal guidelines about social distancing and wearing masks to fight the spread of the virus were emphatically ignored, as, for the most part, were concerns about violating the Hatch Act.
5:57 a.m. Aug. 30, 2020 - By Quentin Fottrell
An analysis of data from 28,000 patients sheds more light on blood-pressure issues and COVID-19 ‘At the start of the pandemic, there was concern that specific medications for high blood pressure could be linked with worse outcomes for COVID-19 patients’‘At the start of the pandemic, there was concern that specific medications for high blood pressure could be linked with worse outcomes for COVID-19 patients.’
10:05 a.m. Aug. 28, 2020 - By Howard Gold
There’s no good replacement for long-term care insurance Alternatives also can be pricey and may not cover what you needAlternatives also can be pricey and may not cover what you need
11:49 a.m. Aug. 25, 2020 - By David Rompf
In a Native American community in Michigan’s Upper Peninsula, COVID-19 has been felt in unexpected ways Temporary tents will be put up in the parking lot of Keweenaw Bay Ojibwa Community College to accommodate some classes, until cold weather sets inTemporary tents will be put up in the parking lot of Keweenaw Bay Ojibwa Community College to accommodate some classes, until cold weather sets in.
10:29 a.m. Aug. 22, 2020 - Associated Press
Coronavirus Latest: World hits grim milestone with 800,000 deaths and close to 23 million confirmed cases U.S. leads the world in deaths, with more than 175,000.The world hit a grim coronavirus milestone Saturday with 800,000 confirmed deaths and close to 23 million confirmed cases.
6:01 a.m. Aug. 21, 2020 - By Paul Brandus
Guess who’s moving in? Mom and Dad Millions of Americans have new roommates: their extended familyMillions of Americans have new roommates: their extended family
4:17 a.m. Aug. 21, 2020 - By Sumathi Reddy
Men now advised to cap alcohol consumption at one drink a day as federal committee rethinks dietary guidelines Data show alcohol consumption on the rise during the coronavirus pandemicData show alcohol consumption on the rise during the coronavirus pandemic.
7:33 p.m. Aug. 20, 2020 - By MarketWatch
Joe Biden’s speech to the Democratic convention: full text Here’s the full text of Joe Biden’s speech accepting the Democratic nomination for president, as prepared for delivery and released by the convention.
11:17 p.m. Aug. 17, 2020 - By Quentin Fottrell
Does sunshine kill coronavirus? Will antibiotics help? These are the most widely shared misconceptions about COVID-19 Six months into the coronavirus pandemic, some people are on edge, while others are just plain confusedSix months into the coronavirus pandemic, some people are on edge, while others are just plain confused.
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