Dow, S& P 500 fight to bring string of gains to three as investors assess vaccine efficacy against omicron

U.S. stock benchmarks traded mixed early Wednesday as investors weighed the efficacy of vaccines and treatments against the omicron variant of coronavirus that causes COVID-19. Pfizer /zigman2/quotes/202877789/composite PFE -1.60% and BioNTech /zigman2/quotes/214419716/composite BNTX +0.26% said Wednesday that a third dose of their CCOVID-19 vaccine neutralized the new strain in lab tests, but that a two-dose regimen was much less effective. The Dow Jones Industrial Average /zigman2/quotes/210598065/realtime DJIA -1.63% was up less than 0.1% at 35,737, and the S&P 500 index /zigman2/quotes/210599714/realtime SPX -1.65% was trading less than 0.1% lower at 4,687. The Nasdaq Composite Index /zigman2/quotes/210598365/realtime COMP -1.60% was down 0.3% at 15,637.

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Add to watchlist PFE

Pfizer Inc.

US : U.S.: NYSE

$ 40.01

-0.65 -1.60%

Volume: 15.44M

March 22, 2023 4:03p

P/E Ratio

7.31

Dividend Yield

4.10%

Market Cap

$228.47 billion

Rev. per Employee

$1.21M

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BioNTech SE ADR

US : U.S.: Nasdaq

$ 133.68

+0.35 +0.26%

Volume: 439,346

March 22, 2023 4:00p

P/E Ratio

2.98

Dividend Yield

0.00%

Market Cap

$32.36 billion

Rev. per Employee

$6.61M

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Add to watchlist DJIA

Dow Jones Industrial Average

US : Dow Jones Global

32,030.11

-530.49 -1.63%

Volume: 0.00

March 22, 2023 5:05p

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S&P 500 Index

US : S&P US

3,936.97

-65.90 -1.65%

Volume: 0.00

March 22, 2023 5:05p

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NASDAQ Composite Index

US : Nasdaq

11,669.96

-190.15 -1.60%

Volume: 5.02B

March 22, 2023 5:16p