BOSTON (MarketWatch) -- Drug stocks staged a healthy rebound from Monday's frightful plunge, with practically all of the large-cap pharmaceutical makers gaining at least 2%. Teva Pharmaceutical Industries /zigman2/quotes/205657894/composite TEVA +12.00% was the Big Pharma standout, as shares rallied 7% to stand at $38.83, while Vertex Pharmaceuticals /zigman2/quotes/202259802/composite VRTX -0.30% was the biggest gainer among the larger-cap biotech issues, up 9% at $43.40. German drug and chemical conglomerate Bayer AG /zigman2/quotes/203424967/delayed BAYRY -0.20% was the notable exception, with shares sliding 2%. The NYSE Arca Pharmaceutical Index was up 2.6% at 296 while the NYSE Arca Biotechnology Index rose 4.1% to 1,109. The Dow Jones Industrial Average /zigman2/quotes/210598065/realtime DJIA -0.36% shot up 211 points to 11,021, after diving 635 points on Monday.